Puerarin is a flavonoid compound, and its structure is characterized by the glucoside of glucose and 7,4'-dihydroxyisoflavone connected by carbon-carbon. Puerarin is the main medicinal ingredient in the root of Pueraria lobata (Puerarialobata), a traditional Chinese medicine plant, with a content of about 2.3%. It also exists in large amounts in the root of Pueraria thunbergiana. Puerarin is extracted from the root of kudzu root.
Physical and chemical properties
Puerarin is white needle-like crystal (methanol-acetic acid), slightly soluble in water, soluble in hot ethanol and ethyl acetate, will not cause hydrolysis of glycosides in alkaline solution, and the characteristic peak wavelength (nm) of ultraviolet absorption is 255 and 400. The CAS number of Puerarin is 3681-99-0.
Safety management
The "Announcement on the Catalog of Names of Cosmetic Raw Materials Used" issued by the State Food and Drug Administration in 2014, and the "Chinese Name Catalog of International Cosmetic Raw Materials Standards" published by CTFA and China Fragrance Association in 2010 all use baicalein as a cosmetic raw material. See reports that it is unsafe for external use.
Application in cosmetics
1. The medicinal use of puerarin is mainly for cardiovascular effects, it can expand coronary arteries, increase coronary flow, stimulate blood circulation, and external use can also promote blood circulation;
2. Puerarin has a strong inhibitory effect on tyrosinase, and it works through the inhibition of tyrosine kinetic enzyme. The dosage in whitening cosmetics is 0.1% to 0.2%;
3. Puerarin can absorb UVA-UVB, which can prevent liver spots and other stains caused by sunlight;
4. Puerarin is easily absorbed by the skin, which can enhance the efficacy of other nutrients and stimulate hair growth. At the same time, it can regulate the skin and increase the moisturizing ability.
