Apigenin is a flavonoid found in various plants and herbs, known for its potential health benefits. From its reputed role in promoting better sleep to its use as a dietary supplement, apigenin has attracted attention for its natural sleep-supporting properties. In this article, we will explore the safety of apigenin supplements, its approval status by the FDA, its effectiveness in improving sleep, its presence in chamomile, the apigenin content in chamomile extract, and the FDA's stance on chamomile extract, all supported by scientific sources.
Is Apigenin Good for Sleep, and Why?
Apigenin has been associated with potential sleep-supporting properties. Research suggests that apigenin may interact with gamma-aminobutyric acid (GABA) receptors in the brain. GABA is a neurotransmitter known for its calming and relaxing effects, and its activation can promote sleepiness and improve sleep quality.
By binding to GABA receptors, apigenin may exert a mild sedative effect, helping to reduce anxiety and induce sleep. However, it is important to note that more extensive research is needed to establish the exact mechanisms of apigenin's sleep-enhancing effects.
Source: Biochemical Pharmacology - https://pubmed.ncbi.nlm.nih.gov/17027980/
Is Apigenin Found in Chamomile?
Yes, apigenin is found in chamomile (Matricaria chamomilla) and some other plants. Chamomile is one of the primary sources of apigenin, making it a popular herbal remedy for its potential calming and sleep-supporting properties.
Source: Journal of Agricultural and Food Chemistry - https://pubs.acs.org/doi/10.1021/jf8014365
How Much Apigenin is Present in Chamomile Extract?
The apigenin content in chamomile extract can vary depending on factors such as the plant's species, growing conditions, and extraction methods. Studies have reported varying concentrations of apigenin in chamomile extracts, with values ranging from 1% to 3% or higher.
Source: Journal of Pharmaceutical and Biomedical Analysis - https://pubmed.ncbi.nlm.nih.gov/26222720/
Is Chamomile Extract or Apigenin supplement Approved by the FDA?
As of the knowledge cutoff date in September 2021, neither chamomile extract nor apigenin supplements have obtained FDA approval as medications or dietary supplements. It is worth noting that chamomile has generally recognized as safe (GRAS) status, allowing its use in food and beverage products due to its safety profile. However, it is essential for individuals considering apigenin supplements or chamomile extract to consult healthcare professionals before use to ensure safety and determine suitable dosages for their specific needs.
Source: U.S. Food and Drug Administration (FDA) - https://www.fda.gov/
