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Cnidium monnieri fruit extract and its Application

2022-11-26 16:38:27

Source of raw materials: Cnidium monnieri, also known as wild fennel, wild carrot, snake rice, snake chestnut, etc., is the dry and mature fruit of Cnidium monnieri, a plant of the family Apiaceae. The main chemical components of Fructus Cnidii are coumarins and volatile oils, as well as compounds such as triterpenes, glycosides, sugars, etc. Among them, coumarins are the main components of Fructus Cnidii to exert pharmacological effects, and their content is relatively high. There are 6 kinds of coumarin compounds used in chemical detection and identification, namely: Osthole, Imperatorin, Isopimpinellin, Xishhotoxin, Bergamot Lactone (Bergaptene) and isoimperatorin. 

 

HerboMate tested and compared the osthole raw materials from all over the country, and finally selected one of the authentic places, the raw materials produced in Xiangfan, Hubei, and required that the osthole content should not be less than 1.2% (calculated as dry products), from the source Product quality is guaranteed.

 

Cnidium seeds benefits at anti-inflammatory

cnidium monnieri fruit extract, Osthole has inhibitory effect on Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli, and can also weaken the pathogenicity of residual strains of Staphylococcus aureus. It can be used synergistically with matrine to treat trichomonal vaginitis, eczema, psoriasis, etc.

 

Cnidium fruit extract, Osthole has an inhibitory effect on Staphylococcus aureus and has a good effect on bacterial inflammation. Combined use of osthole and baicalin to synergistically treat pneumonia caused by Staphylococcus aureus.

 

Cnidium extract function on anticancer

Powder extract of fructus cnidium monnieri, Osthole can inhibit tumor growth in mouse liver cancer model, induce apoptosis of liver cancer cells through multiple targets and multiple pathways, and enhance anti-tumor immune response in mice with liver cancer; osthole can also kill nasopharyngeal cancer cells , lung cancer cells and cervical cancer cells, etc., can inhibit the growth of various tumor cells. It can be used as an auxiliary anti-cancer.

 

Cnidium fruit extract good for Anti-Osteoporosis

Osthole can significantly promote the proliferation and differentiation of bone marrow mesenchymal stem cells and osteoblasts, and at the same time significantly increase the expression levels of osteocalcin and alkaline phosphatase, thereby promoting bone formation, increasing bone mineral content and bone strength. The effect of osthole on promoting the proliferation and differentiation of osteoblasts is related to the concentration, and the optimal concentration is between 5*10-5M-5*10-4M. In addition, the combination of osthole and puerarin can synergistically treat bone dysplasia and osteoporosis.

 

Application of biological pesticides of bulk cnidium extract powder

1. Low content of osthole can be used as botanical pesticides, grain protection agents, etc., and as a pesticide, osthole has passed organic certification and can be used in organic product bases.

2. 1% osthole water emulsion has special effects on melons, strawberries, and flower powdery mildew (the control efficiency is about 95%), and it also has a dual effect on vegetable downy mildew and aphids.

3. 4% osthole powder has a good control effect on corn weevil, trichotilloides, and the adult insects of Tribulus chinensis. Compared with other botanical insecticides, osthole has the advantages of high efficiency and low toxicity.

 

We can offer: cnidium monnieri extract, 10%~98% Osthole

 

Flow Chart - Cindium Extract.pdf


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