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Application of flavonoid rutin at cosmetic

2023-01-20 17:13:56

Rutin is a flavonoid compound, which is the 3-rutinoside of quercetin. It is the main component of sophora japonica fruit of the leguminous plant Sophorajaponica. Sophora buds contains about 20% rutin, and Sophora japonica flowers contains about 8% rutin. Due to the relatively concentrated distribution and content, rutin is the earliest available on a large scale. The flavonoids in the product are not expensive. Rutin can be extracted from Sophora japonica.

Physical and chemical properties

Rutin is light yellow powder. The characteristic peak wavelengths (nm) of ultraviolet absorption are 258 and 361. Rutin is slightly soluble in alcohol and water, and the dilute solution turns green when it encounters ferric chloride. The CAS number of rutin is 153-18-4.

Safety management

The "Announcement on the List of Names of Cosmetic Raw Materials Used" issued by China's State Food and Drug Administration in 2014, and the "List of Chinese Names of International Cosmetic Raw Materials Standards" published by CTFA, the European Union and China Fragrance Association in 2010 all use rutin as a cosmetic raw material , there is no report that it is unsafe for external use.

Application in cosmetics

1, Rutin can strongly absorb ultraviolet rays between 280nm and 335nm, and can be used in sunscreen cosmetics;

2, Rutin has antioxidant properties, which can enhance the efficacy of other cell activators and be used in anti-aging skin care products;

3, Rutin can inhibit the activity of 5α-reductase, and inhibit the secretion of sebum, indicating that it has a good preventive effect on hair loss caused by high androgen, and can be used for hair growth, acne prevention and other products;

4, Rutin has anti-inflammatory properties and can inhibit the activity of phospholipase A2. Phospholipase A2 is a key enzyme for the production of inflammation and allergic mediators in the body, so rutin has anti-allergic effects.


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